Antimalarial Drug Discovery: Andrographis paniculata Leaf Extract
نویسندگان
چکیده
منابع مشابه
Is Andrographis paniculata extract and andrographolide anaphylactic?
Andrographis paniculata, "King of bitters" is a popularly known medicinal plant extensively used in many parts of the world for treatment of various diseases. Since recent past, anaphylactic/allergic type adverse events were reported upon A. paniculata usage, the study aimed to evaluate the anaphylactic and anaphylactoid potential of A. paniculata extract and andrographolide (a major phytoactiv...
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This work was carried out to study the effect of topical application of Andrographis paniculata on the rate of wound enclosure and its histological features. A wound was created in four groups of rat in posterior neck region. Blank placebo was applied topically to the wounds of Group 1. Groups 2 and 3 were dressed with placebo containing 5% and 10% extracts of A. paniculata, respectively. Intra...
متن کاملAndrographis paniculata Leaf Extract Prevents Thioacetamide-Induced Liver Cirrhosis in Rats
This study investigated the hepatoprotective effects of ethanolic Andrographis paniculata leaf extract (ELAP) on thioacetamide-induced hepatotoxicity in rats. An acute toxicity study proved that ELAP is not toxic in rats. To examine the effects of ELAP in vivo, male Sprague Dawley rats were given intraperitoneal injections of vehicle 10% Tween-20, 5 mL/kg (normal control) or 200 mg/kg TAA thioa...
متن کاملHepatoprotective potential of Andrographis paniculata aqueous leaf extract on ethanol . induced liver toxicity in albino rats
To investigate the protective effect of the leaf extract of Andrographis paniculata (Ap) against ethanol induced liver toxicity in male albino rats. The liver toxicity was induced by the administration of ethanol to the animals at the optimum dosage of 7.9g/kg body wt., orally for 45 days. After induction of liver toxicity the aqueous plant extract of A.p was administered to the animal 250 mg/k...
متن کاملAntibacterial Activity of Ethanol Extract of Andrographis paniculata
In the present study the ethanol extract of the aerial part of Andrographis paniculata was prepared and evaluated for antimicrobial activity against eleven bacterial strains by determining minimum inhibitory concentration and zone of inhibition. Minimum inhibitory concentration values were compared with control and zone of inhibition values were compared with standard ciprofloxacin in concentra...
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ژورنال
عنوان ژورنال: Malaria Control & Elimination
سال: 2016
ISSN: 2470-6965
DOI: 10.4172/2470-6965.1000e132